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Shiitake Standardised Extract | Immunity, Vitality and Cholesterol

Defences weaken, cholesterol creeps up, and the daily vitality that once came naturally now needs tending. This isn't inevitable ageing: your immune system needs structural support, not just another supplement.

Shiitake (Lentinula edodes) is the medicinal mushroom with the most democratic clinical evidence in the entire range: a randomised trial in 52 real people documented significant immune improvements at just 4 weeks — with as little as 5-10 g of mushroom per day. Its lentinan is the only active compound derived from a mushroom to be approved as a pharmaceutical adjuvant in Japan.

🛡️ IMMUNITY IN 4 WEEKS: γδ-T cells +60%, NK-T doubled, salivary IgA increased, CRP reduced (RCT, Dai et al. 2015, n=52).

❤️ LIPID PROFILE: eritadenine supports cholesterol metabolism through a different and complementary mechanism to statins.

🌟 VITALITY AND NUTRIENTS: vitamin D2, B12, selenium, zinc — the most complete nutritional profile in the Oravita range

Bottle of 120 Capsules (2 months) - Recommended duration: 6 months

Original price
Original price 74,70 €
24,90 €
24,90 €
Current price 24,90 €
Quantity: 1 bottle
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⭐⭐⭐⭐⭐ This is the second time I buy from this website! Reliable, fast delivery. I have to say, this product does what it's supposed to do. It's the second pack I order and I will order it again... Thank you, RedMoringa! Chantal

Approved by the Ministry of Health

Made in Italy

Only Natural ingredients

With certified dry extracts

ORAVITA by RedMoringa – Shiitake Lentinula edodes Standardised Extract 30% – Immunity | Vitality | Cholesterol

🍄 THE ONLY MEDICINAL MUSHROOM WITH AN ACTIVE COMPOUND APPROVED AS A PHARMACEUTICAL IN JAPAN

The immune system needs structural support. Cholesterol tends to creep up slowly. The daily vitality that was once taken for granted now needs to be cultivated.
Shiitake is the second most cultivated mushroom in the world – and the only one in the Oravita range with a clinical data point obtained with the whole mushroom – not an isolated active compound – in real human beings:

Sluggish immunity – LDL and lipid profile to monitor – reduced daily vitality – weakened mucosal immunity

For those who want the most from a mushroom that is simultaneously centuries-old medicinal food and source of unique natural active compounds, Oravita offers: Lentinula edodes dry extract standardised to 30% polysaccharides (lentinan), with natural eritadenine – the mushroom with the most studied active compound among all medicinal mushrooms, the only one to have received pharmaceutical approval in Japan.

BENEFITS OF ORAVITA SHIITAKE

Lentinula edodes is the mushroom with the most democratic clinical data point in the range: a randomised controlled trial documented significant immune benefits using the food mushroom itself – not a concentrated extract. With the standardised extract, the lentinan dose is guaranteed and reproducible.

🛡️ IMMUNITY DOCUMENTED IN 4 WEEKS

The Dai et al. trial (J Am Coll Nutr, 2015, n=52) with just 5–10 g of dried Shiitake daily for 4 weeks: γδ-T cell proliferation increased by 60%, NK-T doubled (p<0.0001), increased salivary secretory IgA (mucosal immunity), reduced C-reactive protein (systemic inflammatory marker).

❤️ SUPPORTS LIPID PROFILE

Eritadenine is an adenosine analogue found almost exclusively in Shiitake among edible mushrooms. It supports cholesterol metabolism through modulation of the BHMT pathway – a different and complementary mechanism to statins, not competitive.

🌟 VITALITY AND COMPLETE NUTRITIONAL PROFILE

Ergosterol (provitamin D2), vitamin B12, selenium, zinc, copper and manganese: the most complete mineral profile in the Oravita range.


Shiitake – fungo della quercia originario dell'Asia: Lentinano, 30% Polisaccaridi, oltre 2000 anni di storia

WHY THIS EXTRACT IS GENUINELY DIFFERENT

Lentinan is a high-molecular-weight beta-1,3-glucan in triple helix structure extracted from Lentinula edodes. It is the most studied active compound among all medicinal mushrooms – and the only one to have obtained, in Japan, approval as an injectable pharmaceutical adjuvant for advanced gastric cancer in combination with chemotherapy.

An important distinction: this information concerns injectable lentinan in a clinical setting, not oral supplements. Oravita Shiitake is a food supplement. The immunomodulatory properties documented by Dai et al. (2015) were obtained with the mushroom as food – and the standardised extract allows a reproducible dose of active compounds to be taken every day.

A fact few know: lentinan degrades rapidly after harvest and during storage. Fresh supermarket Shiitake contains significantly less lentinan than a standardised extract. With Oravita Shiitake, the declared dose is guaranteed in every capsule.

Shiitake is the only mushroom in the range you can take either as food (cooked, never raw) or as a supplement. Oravita is the choice when you want a precise dose, every day, without depending on the availability of fresh mushroom.

· Plant-based HPMC capsule – suitable for vegans and vegetarians
· Zero magnesium stearate
· No bulking fillers – pure extract only
· Made in Italy with traceable raw materials
· 120 capsules – 2 daily – 60-day course
· Registered with the Ministry of Health

Shiitake capsule ORAVità: difese immunitarie, detox fegato, benessere cardiovascolare e della donna

Ingredients: Shiitake extract (Lentinula edodes (Berk.) Pegler), fruiting body 30% polysaccharides, Coating agent: Hydroxypropylmethylcellulose; corn starch

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Each of our supplements is designed primarily to help with the specific problem. This is a time-consuming process that requires extensive study.

That's why you'll only find a few products in our shop, made with high-quality standardized dry extracts and a large portion of love.

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Questions? We have the answers.

Shiitake edodes: is it the same as Shiitake mushroom?

Yes. Shiitake edodes is a colloquial shortening of Lentinula edodes, the scientifically correct taxonomic name. Previously classified as Lentinus edodes and Cortinellus shiitake, all these names refer to the same species. Oravita uses Lentinula edodes dry extract standardised to 30% polysaccharides (lentinan).

Can raw Shiitake cause a skin rash?

Yes. Shiitake flagellate dermatitis is an inflammatory skin reaction with linear red itchy streaks that can appear 24–48 hours after consuming raw or incompletely cooked Shiitake. It is attributed to native lentinan. Complete cooking inactivates the responsible lentinan. Oravita Shiitake is a dry extract — this specific risk does not apply to the supplement.

How long does Shiitake take to work?

The most robust available RCT (Dai et al., 2015, n=52): immune response (γδ-T cells +60%, NK-T doubled, salivary IgA, CRP reduced): statistically significant at 4 weeks of daily intake. Cholesterol metabolism (eritadenine): observational data suggest at least 6–8 weeks.

Does Shiitake have contraindications?

Anticoagulant therapy (warfarin, DOACs): consult your doctor. Pregnancy and breastfeeding: insufficient data. Autoimmune conditions with immunosuppressants: possible interference. Imminent surgery: discontinue at least 2 weeks prior. Fresh Shiitake in large quantities: may cause digestive difficulties (not applicable to Oravita extract).

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